Course Description
CMB 708 Genetics, Development and Disease (3 credit hours) This project-based component will include studies in DNA repair mechanisms, the basis of selected genetic diseases and pedigree development, study of DNA mutations and treatment options for DNA-based diseases. Students will also explore how alteration of certain metabolic pathways relate to the development and progression of some human diseases. These projects will include the examination of regulations and ethics surrounding treatment and prevention of genetic diseases. Further, students will develop research, writing and presentation skills necessary for the work force.
Course Information
Course Topics
Topics:** Research Project: Ethical Considerations of Genetic Diseases
| Dates |
Assignment |
| IV.1. Autosomal Dominant and Recessive Inheritance |
Assignment: Pedigree Investigation |
| IV.2. Sex Linked and Nontraditional Modes of Inheritance |
Assignment: Colorblindness Study |
| IV.3 Clinical Cytogenetics and Disease |
Assignment: Karyotype Study |
| IV.4. Immunogenetics and Disease |
Assignment: Case Study: SCID – Baby Joe |
| IV.5. Genetic Basis of Development |
Assignment: Sonic Hedgehog and Holoprosencephaly |
| IV.6. Epigenetics |
Assignment: Smoking and Epigenetics (Collaborative) |
| IV.7. Genetic Variation |
Assignment: Hardy Weinberg Problem Set |
| IV.8. Multifactorial Inheritance and Common Disease |
Assignment: Alzheimer Disease and Schizophrenia |
| IV.9. Genetic Testing and Gene Therapy |
Assignment: CRISPR Study |
| IV.10. Genetics and Precision Medicine |
Assignment: GWAS Living in a Genomic World |
**Assignments subject to change.
Grading
Quizzes: 15%
Projects (2): 30% (Rubrics will be used to grade each project)
Written Paper (1): 20%
Case Studies (4): 30% (Rubrics will be used to grade each case study)
Attendance: 5%
Students must maintain a 3.0/4.0 average in the Certificate Program.
